Clinicians need to pay attention to the risk of stroke in sickle cell disease patients, according to a new study.
Research in California, USA, found that rates of stroke have increased over a 30-year period.
The authors say a range of factors could have contributed to this, including a lack of focus on stroke risk among adult patients, failure to implement guidelines, and uncontrolled lifestyle factors.
The landmark STOP trial, published in 1998, found that transcranial doppler screening to identify high risk children and the use of chronic red blood cell transfusions reduced risk of stroke by 90%.
In this new study, the researchers used real-world data to see what impact these recommendations have made in the intervening years, for both...
1 day ago